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The radical possibilities of man-made DNA | Floyd E. Romesberg

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Every cell that's ever lived has been the result of the four-letter genetic alphabet: A, T, C and G — the basic units of DNA. But now that's changed. In a visionary talk, synthetic biologist Floyd E. Romesberg introduces us to the first living organisms created with six-letter DNA — the four natural letters plus two new man-made ones, X and Y — and explores how this breakthrough could challenge our basic understanding of nature's design.

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46 Comments on The radical possibilities of man-made DNA | Floyd E. Romesberg

  1. Discover Your Awesomeness // 17th December 2018 at 5:05 pm // Reply

    *If you don’t design your own life plan, chances are you’ll fall into someone else’s plan. And guess what they have planned for you? Not much..*

  2. 4 thumbs down within 3 minutes of being published for a 13+ minute video…what’s that about? let me guess, Jesus freaks?

    • You don’t need to be abusive to those that have faith, it does you no credit. Whether DNA was the result of evolution or creation, there must be a good reason why the genetic alphabet consists of 4 letters and not 6.

    • Michael Harrison // 17th December 2018 at 6:31 pm // Reply

      Maybe, but this technology may well spend the end for human beings, check out The Revolutinary Phenotype by J F Gariepy.

    • +Michael Harrison that’s sad too… From a universal point if view watching life go out like a light in the cosmos….maybe for no other beings to ever know we were here… Just because we thought we were more intelligent than we actually are.

    • After see this video
      I did think who are jesus ? or who are god?

    • +Paul O’Neill

      You will get to say things when you are capable of doing such things.
      When they are creating DNA with 6 genetic alphabets, they surely know how to do it, how it works,why it works, why we should do it and so on..
      Well, that’s why they call it research.

  3. Quick Fix - Thought Provoking Videos // 17th December 2018 at 5:10 pm // Reply

    The only thing I could think of during the video was trying to grow wings. After the last minutes of it, I just can think of growing green glowing wings…

    • I’d be happy with pocket that can fit things (and technology is much faster than even lab grown biology).

    • The Gospel of Salvation:!/eng
      Please download the PDF file.

      Faith in God = believe God exists and He created everything and sustain everything;
      believe God controls, dictates and tends in the Creation;
      believe God is good and love;
      believe God is a righteous judge;
      believe God is holy; He hates sin;
      believe man sins and needs salvation from sins;
      believe man needs repentance from sins;
      believe God is the only Savior through Jesus Christ; He saves man from sins;
      believe Jesus Christ (Modern Hebrew: Yeshua ha’Mashiach or Ancient Hebrew: YaHuSha ha’Mashiach) is God;
      trust and have hope in God; fear God;
      believe God is a rewarder of those seeking Him (studding the Scriptures and Prayer);
      believe God is a rewarder of those fear Him, love Him and obey Him;
      believe “the reward” is: eternal life in Truth and Love with God;

      Hebrews 11:1 “Now faith is the substance of things hoped for, the evidence of things not seen. (trust and hope in God)”
      Hebrews 11:6 “But without faith it is impossible to please him: for he that cometh to God must believe that He is (God exists), and that he is a rewarder of them that diligently seek him (studding the Scriptures and Prayer; personal relationship with God).”;
      John 14:15 “Jesus speaks: If you love me, keep my commandments.” (obey God)
      Romans 6:23 ”… the wages of sin is death; but the gift of God is eternal life through Jesus Christ our Lord.”
      Isaiah 43:11 “I, even I, am the LORD; and *beside me there is no saviour*.”;
      John 14:6 “Jesus said unto him: *I am the way, the truth, and the life*: no man comes unto the Father, but through me.”
      John 1:1-3 “In the beginning was the Word, and the Word was with God, and the Word was God. The same was in the beginning with God. All things were made by him; and without him was not any thing made that was made.”;
      1 John 5:7 “For there are three that bear record in heaven, the Father (God), the Word (The Son; Jesus Christ), and the Holy Spirit: and these three are one.”
      John 10:30, 38 ”Jesus says:I and my Father are one … the Father is in me, and I in him.”
      John 20:28 “And Thomas answered and said unto Him (Jesus): My Lord and my God.”
      Mark 1:15 “The time is fulfilled, and the kingdom of God is at hand: *repent, and believe the Gospel*.” (Jesus preaching)
      1 Corinthians 15:1-5 ”Moreover, brethren, I declare unto you the Gospel which I preached unto you, which also you have received, and wherein you stand; By which also you are saved, if you keep in memory what I preached unto you, unless you have believed in vain. For I delivered unto you first of all that which I also received, how Christ died for our sins according to the scriptures; And that he was buried, and that he rose again the third day according to the scriptures: And that he was seen of Cephas (Peter), then of the twelve: After that, he was seen of above five hundred brethren at once;” (Apostle Paul preaching)
      Ephesians 2:8-9 ”…by grace you are saved through faith; and that not of yourselves: it is the gift of God: Not of works, lest any man should boast.” (Apostle Paul preaching)
      Acts 20:21 “… Testifying both to the Jews, and also to the Greeks, *repentance toward God*, and *faith toward our Lord Jesus Christ*.” (Apostle Paul preaching)
      Acts 26:20 ”… but declared first to those in Damascus, and at Jerusalem, and throughout all of Judea, and to the nations, that they should *repent, and turn to God, and do works worthy of repentance*.”; (Apostle Paul preaching)
      Ecclesiastes 12:13-14 “Let us hear the conclusion of the whole matter: *Fear God, and Keep His Commandments*: for this is the whole duty of man. For God shall bring every work into judgement, with every secret thing, whether it be good, or whether it be evil.”
      John 17:3 “… And this is *everlasting life*, that they should know You, the only true Elohim, and YaHuSha Messiah whom You have sent …”

      The grace and peace of the Lord Jesus Christ be with you!

    • +MrVazduh I am not sure if that’s supposed to be funny but it dose make me sad.
      Your lord and saviour is associated with many cases of Financial, mental, physical and sexual abuse in community’s that limit growth, independence and the capacity to love and support people one encounters.

    • Sounds like some kind of memetic cognitohazard. Someone call the foundation.

  4. Synthetic life is the logical next step and a great idea for a great tv show called Battlestar Galactica.

  5. Julian Colbert // 17th December 2018 at 5:17 pm // Reply

    This has apocalyptic movie plot written all over it

    • There is a possibility that they would evolve to make thos synthetic chemicals thus making them self sufficient, and then with out natural predators expand like crazy.

    • But even while evolving, they can’t change their DNA from 6 to 4 letters to really interact with nature. Also, evolving takes time…a lot of time 🙂 I dunno i’m not a biologist, but i see more good possibilities than threats.

    • +jamakasis18 the thing is that simple organisms mutate like mad. It’s not unlikely that some of the billion bacteria dumped in the sea mutate and start feeding onto something available.

  6. Who knew the first X-men would be glowing single celled beings 😛

  7. Wow, that guy just answered a question I asked way back when I was a teen. Why only 5? Answer, that’s not the limit!:)
    I can’t see much limit to this technology and so long we don’t lose control of some sort of self-replication new life then the applications are endless. Immortality? Yes! Cure to all exporting maladies? Yes! Travel through space? Yes! Evolving to an higher level of conscience? Yes! And I only scrap the barrel here…

  8. Umbrella corporation!

  9. Devanshu Ballabh // 17th December 2018 at 5:31 pm // Reply

    Can i make xmen using this?

  10. José Coutinho // 17th December 2018 at 5:37 pm // Reply

    So the countdown for Resident Evil IRL has started…

    • Well _these_ Zombies won’t hunt us…. they need synthetic chemicals to live. So they will attack our labs… and McDonald’s?

  11. Interesting and scary at the same time

  12. This is why I’m still subscribed to TED.

  13. So we aren’t gonna get to know the student responsible for growing the first of those cells under the necessary conditions? Where is their credit for this?

  14. logicalempiricist // 17th December 2018 at 6:14 pm // Reply

    Enter Jeff Goldblum the chaos theorist in “Jurrasic Park”:
    “Life finds a way.”

  15. we’re playing with different cards now.

  16. Im so glad to be leaving this world one day!

  17. How would translation even work with these bases? And why do we even need to introduce new bases besides “more options”? Can’t this all be done with the normal 4 bases?

    • The 4 bases is what this world has ever produced, so there is always a possibility that a new drug, for example, doesn’t work as intended due to interference with other molecules before reaching it’s target. But these new base pairs are alien to life on earth, so we can tailor them to go places where normal molecules used to disintegrate before acting.
      Atleast that’s what I have understood from this.

    • What he says is that “more options” means proteins with new amino acids. To me that seems enough.

  18. Transgenic GFP bacteria, C. elegans, even cats, are nothing new…

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